{"id":5265,"date":"2019-02-10T03:59:32","date_gmt":"2019-02-10T05:59:32","guid":{"rendered":"http:\/\/tdibrasil.org\/?p=5265"},"modified":"2021-10-10T03:37:06","modified_gmt":"2021-10-10T06:37:06","slug":"sobre-a-hipotese-do-mundo-de-rna","status":"publish","type":"post","link":"https:\/\/tdibrasil.org\/index.php\/2019\/02\/10\/sobre-a-hipotese-do-mundo-de-rna\/","title":{"rendered":"Sobre a Hip\u00f3tese do Mundo de RNA"},"content":{"rendered":"<figure id=\"attachment_5267\" aria-describedby=\"caption-attachment-5267\" style=\"width: 660px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-5267\" src=\"https:\/\/tdibrasil.org\/wp-content\/uploads\/2019\/02\/RNA-world-1.jpg\" alt=\"\" width=\"660\" height=\"411\" \/><figcaption id=\"caption-attachment-5267\" class=\"wp-caption-text\"><center>Ilustra\u00e7\u00e3o: terra primitiva \/ \u00a9<\/center><\/figcaption><\/figure>\n<hr \/>\n<p>Por\u00a0<strong>Cornelius Hunter <\/strong><span style=\"color: #993300;\"><em>(adapta\u00e7\u00e3o)<\/em><\/span><\/p>\n<p style=\"text-align: justify;\">Dada a sua ampla popularidade e aceita\u00e7\u00e3o voc\u00ea pode n\u00e3o ter percebido que a hip\u00f3tese chamada Mundo de RNA sofre de alguns problemas dram\u00e1ticos.\u00a0No topo da lista est\u00e1 o fato estranho de que n\u00e3o h\u00e1 provas disso.\u00a0Embora os c\u00e9ticos tenham apontado isso h\u00e1 anos, agora vemos os evolucionistas limpando essa verdade inconveniente tamb\u00e9m.\u00a0A saber, aqui est\u00e1 como Peter Wills e Charles Carter abrem seu recente\u00a0<a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0303264717302332\" target=\"_blank\" rel=\"noopener noreferrer\">artigo na\u00a0<em>BioSystems<\/em><\/a>:<\/p>\n<blockquote class=\"tr_bq\">\n<p style=\"text-align: justify;\">O Mundo de RNA \u00e9 um est\u00e1gio hipot\u00e9tico de evolu\u00e7\u00e3o molecular amplamente adotado, desprovido de enzimas proteicas, nas quais todos os catalisadores funcionais eram ribozimas.\u00a0Apenas um fato concernente ao Mundo de RNA pode ser estabelecido pela observa\u00e7\u00e3o direta:<b> se ele existiu, terminou sem deixar nenhum tra\u00e7o inequ\u00edvoco de si mesmo<\/b>.<\/p>\n<\/blockquote>\n<p style=\"text-align: justify;\">Mesmo isso \u00e9 um pouco de subavalia\u00e7\u00e3o.\u00a0Porque sem a suposi\u00e7\u00e3o pr\u00e9via de evolu\u00e7\u00e3o, que pode e tem subscrito uma ampla gama de especula\u00e7\u00e3o, h\u00e1 precisamente uma raz\u00e3o zero para acreditar nesta hip\u00f3tese.\u00a0Nenhum organismo foi descoberto que demonstre a hip\u00f3tese do Mundo de RNA em a\u00e7\u00e3o.\u00a0<strong>Nem cientistas j\u00e1 constru\u00edram tais organismos em seus laborat\u00f3rios<\/strong>.\u00a0Isso n\u00e3o \u00e9 muito surpreendente, porque ningu\u00e9m produziu <strong>nada remotamente pr\u00f3ximo a um projeto detalhado de como esses organismos poderiam funcionar<\/strong>.<\/p>\n<p style=\"text-align: justify;\">Wills e Carter tamb\u00e9m\u00a0<a href=\"https:\/\/www.sciencedaily.com\/releases\/2017\/11\/171101160756.htm\" target=\"_blank\" rel=\"noopener noreferrer\">apontam<\/a>\u00a0evid\u00eancias negativas, como a cat\u00e1lise (as enzimas do RNA n\u00e3o t\u00eam a capacidade de funcionar em uma ampla faixa de temperaturas) e os \u201cobst\u00e1culos imposs\u00edveis\u201d \u00e0 transi\u00e7\u00e3o hipot\u00e9tica, mas necess\u00e1ria, do Mundo do RNA para algo semelhante \u00e0s c\u00e9lulas atuais.\u00a0Como Carter explica:<\/p>\n<blockquote class=\"tr_bq\">\n<p style=\"text-align: justify;\">Tal transi\u00e7\u00e3o do RNA para a vida baseada em c\u00e9lulas teria exigido um repentino aparecimento de uma prote\u00edna do tipo aaRS [aminoacil-tRNA sintetase] que funcionou ainda melhor do que sua contraparte de RNA adaptada.\u00a0Esse evento extremamente improv\u00e1vel teria que acontecer n\u00e3o apenas uma vez, mas v\u00e1rias vezes &#8211; uma vez que existe uma para cada amino\u00e1cido no c\u00f3digo gen\u00e9tico.\u00a0<b>Isso simplesmente n\u00e3o faz sentido<\/b>\u00a0.<\/p>\n<\/blockquote>\n<p style=\"text-align: justify;\">De fato, isso simplesmente n\u00e3o faz sentido.\u00a0E ainda, apesar desses problemas \u00f3bvios, o Mundo de RNA tem sido um artigo fundamental, apresentado como um exemplo plaus\u00edvel e prov\u00e1vel de como a vida inicial evoluiu.<\/p>\n<hr \/>\n<p>Original: <strong>Cornelius Hunter<\/strong>. <a href=\"https:\/\/evolutionnews.org\/2018\/01\/about-that-rna-world-hypothesis\/\" target=\"_blank\" rel=\"noopener noreferrer\">About That RNA World Hypothesis<\/a>. January 23, 2018.<\/p>\n","protected":false},"excerpt":{"rendered":"<div class=\"mh-excerpt\"><p>Por\u00a0Cornelius Hunter (adapta\u00e7\u00e3o) Dada a sua ampla popularidade e aceita\u00e7\u00e3o voc\u00ea pode n\u00e3o ter percebido que a hip\u00f3tese chamada Mundo de RNA sofre de alguns <a class=\"mh-excerpt-more\" href=\"https:\/\/tdibrasil.org\/index.php\/2019\/02\/10\/sobre-a-hipotese-do-mundo-de-rna\/\" title=\"Sobre a Hip\u00f3tese do Mundo de RNA\">[&#8230;]<\/a><\/p>\n<\/div>","protected":false},"author":1,"featured_media":5267,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[25,40],"tags":[639,640],"class_list":["post-5265","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-geral","category-traducao","tag-mundo-de-arn","tag-mundo-de-rna"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v18.9 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Sobre a Hip\u00f3tese do Mundo de RNA &raquo; 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